Central Nervous System
CNS acting drugs have a major therapeutic & clinical importance, Drugs can produce diverse pharmacological & Psychological effects. Don Valley Pharma is a leading central nervous system drugs manufacturer in Pakistan.
Generic: Quetiapine (as fumarate)
Composition: 100mg/Tablet
Generic: Quetiapine (as fumarate)
Composition: 300mg/Tablet
Generic: Sodium Valproate
Composition: 200mg/Tablet
Generic: Sodium Valproate
Composition: 500mg/Tablet
Generic: Sodium Valproate
Composition: 250mg/5ml
Generic: Escitalopram (as oxalate)
Composition: 5mg/Tablet
Generic: Escitalopram (as oxalate)
Composition: 10mg/Tablet
Generic: Levosulpiride
Composition: 25mg/Tablet
Generic: Levosulpiride
Composition: 50mg/Tablet
Generic: Duloxetine
Composition: 20mg/Capsule
Generic: Duloxetine
Composition: 30mg/Capsule
Generic: Clonazepam
Composition: 0.5mg/Tablet
Generic: Clonazepam
Composition: 0.5mg/Tablet
Other Central Nervous System Products
Sr. # | Brand Name/Form | Generic/Composition | Pack Size |
---|---|---|---|
1 | Angepine Tablets | Each Tablet contains: Quetiapine (as fumarate)……………………..……..25mg | 30's |
2 | Angepine Tablets | Each Tablet contains: Quetiapine (as fumarate)…………………………..100mg | 30's |
3 | Angepine XR Tablets | Each Tablet contains: Quetiapine (as fumarate)…………………………..300mg | 10's |
4 | Easrin Tablets | Each Tablet contains: Aliskiren (as hemifumarate)………………………150mg | 7's |
5 | Easrin Tablets | Each Tablet contains: Aliskiren (as hemifumarate)………………………300mg | 7's |
6 | Eziness Capsules | Each Capsule contains: Duloxetine (as HCI)……………………………….…20mg | 10's |
7 | Eziness Capsules | Each Capsule contains: Duloxetine (as HCI)……………………………….…30mg | 10's |
8 | Eziness Capsules | Each Capsule contains: Duloxetine (as HCI)……………………………….…60mg | 10's |
9 | Fluxine Capsules | Each Capsule contains: Fluoxetine……………………………………….……20mg | 7's, 14's & 28's |
10 | Leptil Tablets | Each Tablet contains: Sodium Valproate……………………………….…200mg | 50's & 100's |
11 | Leptil Tablets | Each Tablet contains: Sodium Valproate……………………………….…300mg | As per Requirement |
12 | Leptil Tablets | Each Tablet contains: Sodium Valproate……………………………….…500mg | 50's & 100's |
13 | Leptil Syrup | Each 5ml contains: Sodium Valproate………………………………….250mg | 60ml & 150ml |
14 | Leptil Syrup | Each 5ml contains: Sodium Valproate………………………………….200mg | As per Requirement |
15 | DV-Lopram Tablets | Each Film Tablet contains: Escitalopram (as oxalate)…………………………….5mg | As per Requirement |
16 | DV-Lopram Tablets | Each Film Tablet contains: Escitalopram (as oxalate)………………………..….10mg | As per Requirement |
17 | DV-Lopram Tablets | Each Film Tablet contains: Escitalopram (as oxalate)………………………..….20mg | As per Requirement |
18 | DV-Leo Tablets | Each Tablet contains: Levosulpiride……………………………………..…..25mg | As per Requirement |
19 | DV-Leo Tablets | Each Tablet contains: Levosulpiride……………………………………..…..50mg | As per Requirement |
20 | DV-Traline Tablets | Each Film Tablet contains: Sertraline (as HCI)……………….……………….….50mg | As per Requirement |
21 | DV-Traline Tablets | Each Film Tablet contains: Sertraline (as HCI)……………….……………...….100mg | As per Requirement |
22 | DV-Clonaz Tablets | Each Film Tablet contains: Clonazepam……..……………….………………….0.5mg | As per Requirement |
23 | DV-Clonaz Tablets | Each Film Tablet contains: Clonazepam……..……………….………………...….1mg | As per Requirement |
24 | Alpraz Tablet 2mg | Each uncoated Tablet contains: Alprazolam……..……………….………………...….10mg | As per Requirement |
25 | Diaz Tablet 10mg | Each uncoated Tablet contains: Diazepam……..……………….………………...….10mg | As per Requirement |
26 | Oxycode Tablet 80mg | Each Tablet contains: Oxycodone……..……………….………………...….80mg | As per Requirement |
Best CNS Drugs Manufacturer in Pakistan
What are CNS drugs?
There are two categories for CNS drugs
CNS depressants & CNS stimulants
CNS Depressants
Central Nervous System (CNS) depressants are medicines that include sedatives, tranquilizers, and hypnotics. These drugs can slow brain activity, making them useful for treating anxiety, panic, acute stress reactions, and sleep disorders.
CNS Stimulants
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase the activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.
Why are they prescribed?
CNS acting drugs have a major therapeutic & clinical importance, Drugs can produce diverse pharmacological & Psychological effects such as:
- Induction of Anesthesia
- Relief of Pain
- Prevention of Epileptic seizures
- Reduction of Anxiety
- Treatment of Depression
- Treatment of Alzheimer’s disease & Parkinsonism
Examples:
Sedatives, Tranquilizers, Hypnotics, Anesthetics, Anticonvulsants, Analgesics, Psychotropic agents, Behavioral modifying drugs.
Examples of CNS drugs available in Pakistan:
Alprazolam, Diazepam, Valproate Sodium, Sertraline, Lamotrigine, Methylphenidate etc
Central Nervous System Stimulants Manufacturer in Pakistan
1- Cerebral stimulants (Cerebral -cortex stimulants)
Stimulate motor & sensory areas to increase physical & mental wakefulness, refreshment, and decrease fatigue. Awake animals from anesthesia in Vet. Med.
Caffeine (coffee seeds), theophylline (tea leaves)
Examples:
Theobromine (coca seeds) & methylated Xanthine, Methylxanthines derivatives, Amphetamine
Pharmacological effects
- Stimulates CNS, decreases fatigue and increases motor activity.
- Stimulates the heart and causes vasodilation.
- Relaxation of smooth muscle therefore theophylline is used in asthma.
- The diuretic effect through increasing renal blood flow.
- Stimulation of gastric acid secretion.
2- Medullary stimulants Drugs
Stimulate centers of M.O. especially depressed resp. C. Awake anesthetized animal by stim.brain & M.O. centers.
Powerful stimulant on respiratory & vasomotor centers.
Raised blood pressure & increased respiration.
Examples:
Doxapram, Cardiazol, Picrotoxine, Pentylenetetrazole
Pharmacological effects
- Antagonizes the respiratory depressant action of Barbiturates.
- Antagonizes the sedative action of xylazine.
3- Spinal cord Stimulants
Mechanism of action
Antagonizes glycine receptors in the spinal cord.
Examples
Strychnine
Indications
- Improves appetite in very small quantities.
- Used as a tonic.
- Kill the stray dogs.
Central Nervous System Depressants Manufacturer in Pakistan
1- Nerve Sedatives/ Hypnotics
Sedatives work by modifying certain nerve communications in your central nervous system (CNS) to your brain. In this case, they relax your body by slowing down brain activity.
Specifically, sedatives make the neurotransmitter called gamma-aminobutyric acid (GABA trusted Source) work overtime. GABA is responsible for slowing down your brain. By upping its level of activity in the CNS, sedatives allow GABA to produce a much stronger effect on your brain activity.
Types of sedatives
Benzodiazepines
Examples of drugs
Alprazolam, Lorazepam, Diazepam
What they treat
They are used in the treatment of anxiety
Panic disorders, sleep disorders
2- Tranquilizers
Hypnotics (non-benzodiazepines)
Examples of drugs
Zolpidem
What they treat
They are used in the treatment of sleep disorders
3- Anticonvulsants
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder since many seem to act as mood stabilizers and for the treatment of neuropathic pain. Anticonvulsants suppress the excessive rapid firing of neurons during seizures. Anticonvulsants also prevent the spread of the seizure within the brain
Examples:
Phenytoin, valproic acid, phenobarbital, lamotrigine, carbamazepine, topiramate, oxcarbazepine, zonisamide
4- Anesthetics
Barbiturates
Examples of drugs
Pentobarbital sodium, phenobarbital
What they treat
They are used in the treatment of anesthesia
5- Analgesics
Opioids/Narcotics
Examples of drugs
Hydrocodone/acetaminophen, oxycodone, oxycodone/acetaminophen
What they treat
They are used in the treatment of pain.